PLASMA APOLIPOPROTEIN E LEVELS IN HYPERLIPIDEMIA
نویسندگان
چکیده
منابع مشابه
Segregation analysis of plasma apolipoprotein B levels in familial combined hyperlipidemia.
Familial combined hyperlipidemia (FCH) is a heritable lipid disorder that is associated with an increased risk of premature cardiovascular disease. An elevated plasma apolipoprotein (apo) B concentration is reported to be a diagnostic feature of the disorder. Recently we demonstrated a strong relation between plasma apoB concentrations and the cholesterol concentration in VLDL plus LDL, both el...
متن کاملApolipoprotein E polymorphism affects plasma levels of lipoprotein(a).
In a group of 303 healthy Caucasian adults of both sexes we studied the influence of the apolipoprotein E (apo E) polymorphism on plasma levels of Lipoprotein(a) (Lp(a). The APOE*2 allele was found to decrease the mean plasma Lp(a) level by 24.8%, whereas the APOE*4 allele increased the mean Lp(a) level by 25.7%. These effects were parallel to the effect of apo E polymorphism on plasma choleste...
متن کاملBiochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia.
Apolipoprotein A-II (apoA-II) is a major protein on high-density lipoprotein (HDL) particles, and in mice, its levels are associated with triglyceride and glucose metabolism. In particular, transgenic mice overexpressing apoA-II exhibit hypertriglyceridemia, increased body fat, and insulin resistance, whereas apoA-II-null mice have decreased triglycerides and increased insulin sensitivity. Give...
متن کاملCerebrospinal Fluid Apolipoprotein E Levels in Delirium
BACKGROUND/AIMS Delirium and the apolipoprotein E ε4 allele are risk factors for late-onset Alzheimer disease (LOAD), but the connection is unclear. We looked for an association. METHODS Inpatients with delirium (n = 18) were compared with LOAD outpatients (n = 19), assaying blood and cerebrospinal fluid (CSF) using multiplex ELISA. RESULTS The patients with delirium had a higher Confusion ...
متن کاملFABP4 plasma levels are increased in familial combined hyperlipidemia.
The lipid profile of familial combined hyperlipidemia (FCHL) shares some characteristics with atherogenic dyslipidemia seen in diabetes, metabolic syndrome, and obesity. Adipocyte fatty acid-binding protein 4 (FABP4) appears to be a determinant of atherogenic dyslipidemia. We examined relationships between FABP4 plasma concentrations, dyslipidemia, and metabolic variables in patients with FCHL....
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 1981
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.70.1249